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TMJ Diseases & Disorders - Scientific Research - Research Grant Opportunities

Research Grant Opportunities

Probes and Instrumentation for Monitoring and Manipulating Nervous System Plasticity (R01)(RFA-MH-09-030)

Release/Posted Date: March 19, 2008
Opening Date: August 16, 2008 (Earliest date an application may be submitted to Grants.gov)
Letters of Intent Receipt Date(s): August 16, 2008
Expiration Date: September 17, 2008

http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-09-030.html.
This Funding Opportunity Announcement (FOA) is issued as an initiative of the NIH Blueprint for Neuroscience Research. The Neuroscience Blueprint is a collaborative framework through which 16 NIH Institutes, Centers and Offices jointly support neuroscience-related research, with the aim of accelerating discoveries and reducing the burden of nervous system disorders (for further information, see http://neuroscienceblueprint.nih.gov/). Applications are solicited for support of projects that will develop probes, instrumentation, and other tools for understanding, monitoring, and manipulating nervous system plasticity. This FOA will focus on the development of tools or techniques that will significantly advance the current state of the art in neuroplasticity research. Although applications will not be restricted to a particular type of technology, we are especially interested in applications that seek to harness the ability to assess and manipulate activity with exquisite subcellular resolution, and in cells specified by their circuit connectivity and/or transmitter phenotype.

NIAMS Building Interdisciplinary Research Team (BIRT) Revision Awards - RFA) Number: RFA-AR-08-001

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Released Date: November 2, 2007

http://grants2.nih.gov/grants/guide/rfa-files/RFA-AR-08-001.html.
To promote interdisciplinary research, the NIAMS plans to provide up to 1 year of research revision support (formerly referred to as “supplement” – see page 1-21 section 2.8 of the SF424 (R&R) Application and Electronic Submission Instructions Version 2) to active NIAMS R01s (parent grants) to establish collaborations among groups of investigators with expertise in the specific areas listed below. The institute intends to supplement interdisciplinary collaboration with high innovation and potentially high impact in the specific NIAMS mission–relevant areas solicited in this FOA. It is understood that such an application may entail high risk. Teams developed under this award are expected to make significant advances beyond the progress expected from the individual researchers alone. Collaborations between scientific areas listed below are selected to pilot the NIAMS BIRT awards and specifically solicited in this FOA.

Autoimmunity – Gender and sex factors
Autoimmunity or Developmental biology – Systems biology
Soft tissue biology – Imaging technologies
Tissue engineering – Immunology or Developmental biology

Translational Application of Gene Silencing Strategies to Oral and Craniofacial Disorders (R21)

National Institute of Dental and Craniofacial Research
Release/Posted Date: September 13, 2007
Opening Date: October 26, 2007 (Earliest date an application may be submitted to Grants.gov)
Letters of Intent Receipt Date(s): November 1, 2007; November 1, 2008
Expiration Date: November 27, 2008

http://grants.nih.gov/grants/guide/rfa-files/RFA-DE-08-005.html.
The primary objective of this FOA is to enhance translational research within the mission areas of the NIDCR by harnessing oligonucleotide-based approaches such as RNA interference (RNAi) to modify the expression of genes associated with oral, dental, and craniofacial diseases and disorders. These diseases are complex conditions involving multiple genes and gene-environmental interactions. The ability to selectively silence or modify gene expression is fundamental to understanding complex disease processes and to developing possible therapeutics and prevention strategies. Research proposing to apply RNAi and other oligonucleotide-based strategies can provide rapid and efficient methods for developing new therapeutics for the prevention and treatment of many oral and craniofacial disorders. Applicants should demonstrate that the proposed oligonucleotide-based approaches directly influence molecular, biochemical, electrophysiological or other functional changes in a condition that falls within the NIDCR mission area. These areas include tooth and bone disorders, oral cancer, chronic inflammatory conditions, viral infections, autoimmune disorders, craniofacial birth defects, acute and chronic pain conditions, salivary gland dysfunction, as well as other oral, dental and craniofacial disorders (see http://www.nidcr.nih.gov). Eligible applications may include a component proposing technological innovations to improve the efficiency of delivery, specificity, processing or stability of the oligonucleotide-based strategy, but the proposal must be focused on an oral, dental, or craniofacial health problem. Applications must include a detailed discussion of strategies to assess and minimize nonspecific and off-target effects such as the silencing or induction of unintended targets, as well as potential immune responses triggered by the intervention. Studies that use human samples, animal models, or tissue culture cells are considered appropriate in response to this FOA.

The Biomarkers Consortium

The Biomarkers Consortium, a research partnership managed by the Foundation for the National Institutes of Health, is soliciting concepts for biomarker projects. Researchers are encouraged to submit project concepts online at http://www.biomarkersconsortium.org. If a concept is approved for development by the consortium, the Foundation for NIH will seek funds to support the project.

The consortium is a large-scale, public-private research partnership formed in 2006 to identify and qualify biomarkers. It encourages participation by academia, government, industry, patient advocacy groups and other non-profit organizations. In addition to the Foundation for NIH, founding members of the consortium include the NIH, the Food and Drug Administration and the Pharmaceutical Research and Manufacturers of America.

Information about the Foundation for NIH is available at http://www.fnih.org. A news release about the consortium’s call for biomarker project concepts is available at: http://www.fnih.org/news/biomarkers_web_site.shtml

US-JAPAN Brain Research Cooperative Program - US Component, NOT-NS-07-009

National Institute of Dental and Craniofacial Research
Released Date: May 3, 2007
Receipt Dates: September 15, 2007, 2008, 2009
Earliest Anticipated Start Date: February 1, 2008

http://grants1.nih.gov/grants/guide/notice-files/NOT-NS-07-009.html.
This Notice is to inform potential applicants that the NIH is once again accepting applications for the U.S. component of the U.S. – Japan Brain Research Cooperative Program (BRCP). The purpose of the BRCP is to promote scientist exchange, training, and research collaborations between neuroscientists from the U.S. and Japan. The U.S. component of the BRCP supports the following activities: 1) Visit of U.S. scientists to conduct collaborative research and/or to acquire advanced research skills in Japanese institutions, 2) Joint workshops to exchange scientific information and to foster collaborations. Areas of research interests of the participating NIH Institutes The NIDCR supports research on molecular mechanisms regulating normal craniofacial development; genetic and environmental influences on abnormal craniofacial disorders; and the etiology and pathophysiology of chronic pain in orofacial tissues with a focus on the temporomandibular joint.